Epidemiology
Coronary Artery Disease in Diabetic PatientsCoronary Artery Disease in Diabetic Patients
Key Point
- Diabetic patients with CAD should receive statin therapy.
Complications of diabetes mellitus include large vessel atherosclerosis leading to myocardial ischemia, myocardial infarction, stroke, and renal failure. Control of hypertension and dyslipidemia can significantly reduce the risk of cardiovascular events. Cardiovascular event rates are increased in insulin-resistant patients, even in those without frank diabetes mellitus. Patients with diabetes who experience myocardial infarction have poorer outcomes with regard to long-term survival than nondiabetic patients.
43. Collins R, Armitage J, Parish S, Sleigh P, Peto R. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963
people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005-16. [PMID: 12814710]
44. Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status. J Am Coll Cardiol. 2000;35:1122-9. [PMID: 10758950]
45. Sobel BE, Frye R, Detre KM, . Burgeoning dilemmas in the management of diabetes and cardiovascular disease: rationale for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. Circulation. 2003;107:636-42. [PMID: 12566379]
44. Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status. J Am Coll Cardiol. 2000;35:1122-9. [PMID: 10758950]
45. Sobel BE, Frye R, Detre KM, . Burgeoning dilemmas in the management of diabetes and cardiovascular disease: rationale for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial. Circulation. 2003;107:636-42. [PMID: 12566379]
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