Page 2: Cardiovascular Medicine, Acute Coronary Syndromes (STEMI, NSTEMI, and Unstable Angina), Testing. In the second Study Table, "ECG Localization of STEMI," the entry for "Indicative ECG Leads" for the right ventricle has been revised to, "V4R-V6R and occasionally V1” (“tall R waves in V1-V3” has been removed); additionally, "and/or lateral" has been removed from the footnote, which now reads, "Often associated with inferior ST-elevation infarctions." (Added October 2020)
Page 14: Cardiovascular Medicine, Sinus Bradycardia and Heart Block, Diagnosis. In the sentence reading, “Sinus bradycardia occurs when the AV nodal impulses fire at a rate lower than expected (less than 60/min),” the term "AV nodal" should be "SA nodal." (Added October 2021)
Page 21: Cardiovascular Medicine, Supraventricular Tachycardia, Diagnosis. In the algorithm, "Classification of Narrow-Complex Tachycardia," under "Regular rhythm," the far right box should read "Long RP interval," not "Log." (Added October 2020)
Page 45: Cardiovascular Medicine, Thoracic Aortic Aneurysm and Dissection, Treatment and Follow-up. The first bullet point in the Treatment section should read, "aortic diameter >5.5 cm (>4.5-5.0 cm for Marfan syndrome)". The Follow-up section should read, "Annual echocardiography is recommended if the aortic diameter has been stable and <5.0 cm. If the aortic diameter is ≥5.0 cm or the rate of enlargement is >0.5 cm/year, imaging should be performed every 6 months." (Added March 2019)
Page 110: Gastroesophageal Reflux Disease, Diagnosis. The sentence stating, "In patients without alarm features...symptom relief with PPI therapy confirms the diagnosis," the word "confirms" has been revised to "supports." (Added March 2019)
Page 129: Gastroenterology and Hepatology, Hepatitis B, Treatment. In the paragraph beginning, “Treatment usually consists of…” the second sentence should state, “Pegylated interferon may be used for patients…who are not pregnant.” (Added September 2019)
Page 145-146: General Internal Medicine, Biostatistics, Risk Estimates. In the Study Table: Common Calculations Used in Clinical Research, the calculation for “Number needed to harm (NNH)” should be “NNH = 1/ARI.” In the table cell for Notes, the following should be added, “ARI is the absolute risk increase and equals | EER – CER | when the event is an unfavorable outcome (e.g., drug side effect).” (Added September 2019)
Page 150: General Internal Medicine, Alcohol Use Disorder, Screening. The second sentence has been corrected to state, "Patients with AUDIT-C scores ≥4 for men and ≥3 for women or a CAGE questionnaire score >1 are candidates for further evaluation and intervention." (Added March 2019)
Page 171: General Internal Medicine, Cervical Cancer Screening, Screening. The last sentence of the first paragraph listing high-risk HPV genotypes should state, "High-risk HPV is defined as genotypes 16 and 18..." (Added March 2019)
Page 270: Nephrology, Hyponatremia, Diagnosis. In the Study Table: Evaluating Hypo-osmolar Hyponatremia, 4th row, under the Laboratory Studies heading, the Spot Urine Sodium value should be <20 mEq/L. (Added March 2019)
Page 274: Nephrology, Approach to Acid-Base Problem Solving, Delta-Delta. In the first sentence of the section, the equation for change in anion gap is incorrect. The sentence should read, "In anion gap acidosis, the expected ratio between the change in anion gap (measured anion gap−normal anion gap)..." (Added October 2020)
Page 296: Neurology, Primary Headaches, Thunderclap Headaches. In the first sentence of the section, "thunderclap" headache should be defined as reaching maximum intensity within 1 to 60 minutes. (Added March 2020)
Page 298: Neurology, Epilepsy, Diagnosis, Study Table. In the Study Table, "Common Epilepsy Syndromes," the last sentence describing temporal lobe epilepsy should state, "Mesial temporal lobe sclerosis..." not "medial." (Added October 2020)
Page 303: Neurology, Subarachnoid Hemorrhage, Diagnosis. In the fourth sentence of the paragraph, which begins "Most patients present to the emergency department…" should finish with the statement "(reaches maximal intensity in 1 to 60 minutes)." (Added March 2020)